Knock, Knock to Reset the Clock: Mechanosensation and Circadian Rhythms
نویسندگان
چکیده
منابع مشابه
Rhythms in Energy Storage Control the Ability of the Cyanobacterial Circadian Clock to Reset
Circadian clocks are oscillatory systems that schedule daily rhythms of organismal behavior. The ability of the clock to reset its phase in response to external signals is critical for proper synchronization with the environment. In the model clock from cyanobacteria, the KaiABC proteins that comprise the core oscillator are directly sensitive to metabolites. Reduced ATP/ADP ratio and oxidized ...
متن کاملModel-based Predictions of the Influence of Circadian Clock Genes Knock-Outs on the Cell Cycle
The existence of links between the cell division cycle and the circadian clock has been recently discovered. In this research report, we perform a small in silico analysis of how mutations on the clock genes composing the mammalian circadian clock affect the phenotype of the cell cycle. For this purpose, we use a coupled model of the mammalian circadian clock and the mammalian cell cycle where ...
متن کاملCircadian rhythms: Eyes of the clock
The daily light-dark cycle synchronizes the internal circadian clock with the outside world. Blind organisms maintain this light-induced entrainment, suggesting the existence of a non-visual phototransduction pathway. The photoreceptor is unknown, but several intriguing candidates have recently come to light.
متن کاملCircadian Rhythms: Hijacking the Cyanobacterial Clock
Using basic research to advance a practical application, a recent study demonstrates that the circadian clock in cyanobacteria can be 'reprogrammed' to improve yields of heterologous protein production - a green future surely beckons.
متن کاملMolecular clock mechanisms and circadian rhythms intrinsic to the heart.
Circadian rhythms are the external expression of an internal clock mechanism that measures daily time.1 Periodic environmental cues entrain or set the circadian clocks. The daily light-dark cycle represents the most dominant and potent entraining stimulus in mammals. An entrained clock coordinates physiological events to the 24hour day. Normally, cardiovascular or hemodynamic parameters, such a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2014
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2014.04.011